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Photoaging or photoageing (also known as "dermatoheliosis") is a term used for the characteristic changes to skin induced by chronic UVA and UVB exposure. Tretinoin is the best studied retinoid in the treatment of photoaging -- Wikipedia

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Effect of Use of Platelet-Rich Plasma (PRP) in Skin with Intrinsic Agi

Treatment with PRP increased reticular dermis thickness with a fibrotic aspect. In the long term, the presence of inflammation and microangiopathy caused by PRP injection could lead to trophic alteration of the skin and
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Hyperpigmentation - Wikipedia

Hyperpigmentation is the darkening of an area of skin or nails caused by increased melanin.
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